… polymerase μ and λ to add nucleotides; and the DNA ligase IV … The reported values are
averages of three independent … Artemis, DNA-PK cs , and X4·LIV were not sufficient for NHEJ of …

… this short-range NHEJ complex requires DNA ligase IV (Lig4), … Lig4 complex promotes the
activity of DNA ligase III (Lig3). … of the ligase complex (but not its ligase activity) is sufficient to …

… The classical NHEJ pathway, of which DNA Ligase IV is a … with or without developmental
delay, are sufficient to confirm a rare … The third enzyme that makes up the NHEJ ligation enzyme …

… in NHEJ and is performed by one of the three mammalian … This NHEJ core complex is
sufficient to physically link a pair of … Repair of NHEJ substrates was severely reduced in LIG4À/À …

… NHEJ. For example, in immunoglobulin class switch recombination, when DNA ligase IV is
missing, DNA ligase I or DNA ligase III … were sufficient to induce non-physiological levels of ∼…

… in NHEJ, followed by the iterative binding of nucleases, DNA … X4-LIV alone is sufficient to
stimulate Artemis endonuclease … DNA ligases I, III, and IV share features conserved in all DNA …

… of DNA ligase IV (Lig4), a core component of the NHEJ … Vertebrates have three ATP-dependent
DNA ligases (Lig1, Lig3, and … only DNA ligase left in Lig1 −/− Lig4 −/− cells) is sufficient to …

… interactions of the NHEJ-specific DNA Ligase IV (Lig4) within … Ku and DNA-PKcs are sufficient
for LR complex formation, but other … For this purpose, we developed a three-color single-…

… have lower levels of mitochondrial DNA ligase IIIα, … NHEJ proteins including DNA PKcs
and DNA ligase IV/XRCC4. While these three core components are sufficient to join duplex DNA …

… DNA ligases III and IV (LIG3, LIG4) have long been credited … by 14 bp of duplex DNA were
found to be of sufficient length, … reaction reached saturation at low concentrations of the 3′-…